{"id":229608,"date":"2025-02-25T11:01:13","date_gmt":"2025-02-25T10:01:13","guid":{"rendered":"https:\/\/www.qualipath.de\/nuertingen\/?page_id=229608"},"modified":"2025-06-12T08:13:23","modified_gmt":"2025-06-12T06:13:23","slug":"prof-dr-med-bence-sipos","status":"publish","type":"page","link":"https:\/\/www.qualipath.de\/nuertingen\/team\/aerzte-team\/prof-dr-med-bence-sipos\/","title":{"rendered":"Prof. Dr. med. Bence Sipos"},"content":{"rendered":"

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Prof. dr. med. Bence Sipos<\/strong><\/h1>\n

<\/h1>\n

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Gesellschafter Qualipath<\/strong><\/h3>\n

Facharzt f\u00fcr Pathologie
\nMolekularpathologie
\nFachbezogene Humangenetische Beratung<\/strong><\/h3>\n

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Vita<\/h2>\n

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STUDIUM<\/strong><\/h4>\n

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1984-1990 Semmelweis Universit\u00e4t. Budapest, Ungarn (Humanmedizin)<\/p>\n

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FACHARZT<\/strong><\/h4>\n

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1994 Facharzt f\u00fcr Pathologie und Zytopathologie, Ungarn<\/p>\n

2001 Facharzt f\u00fcr Pathologie, Deutschland<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=“1_3,2_3″ _builder_version=“4.27.4″ _module_preset=“default“ width=“90%“ custom_margin=“||||false|false“ custom_padding=“||0px||false|false“ locked=“off“ global_colors_info=“{}“][et_pb_column type=“1_3″ _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“][et_pb_text _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“]<\/p>\n

HABITILATION<\/strong><\/h4>\n

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2006 Venia legendi f\u00fcr Pathologie, Med. Fakult\u00e4t, Christian Albrechts Universit\u00e4t, Kiel
\u201eExperimentelle Modelle und morphologisch-funktionelle Untersuchungen zur Angio- und Lymphangiogenese in Pankreastumoren\u201c<\/p>\n

2008 Ruf \u201eAssistenzprofessur f\u00fcr Molekulare Pathologie\u201c (tenure Track) am Institut f\u00fcr Klinische Pathologie, Universit\u00e4t Z\u00fcrich<\/p>\n

2008 Ruf W3-Professur (ohne Leitungsfunktion) f\u00fcr Tumorpathologie am Institut f\u00fcr Pathologie, Eberhard-Karls-Universit\u00e4t, T\u00fcbingen<\/p>\n

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BERUFLICHER WERDEGANG<\/strong><\/h4>\n

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1990-1998 Assistenzarzt am II. Institut f\u00fcr Pathologie, Semmelweis Universit\u00e4t Budapest, Ungarn<\/p>\n

1998-1999 \u201eE\u00f6tv\u00f6s\u201c Studium am Institut f\u00fcr Pathologie, Universit\u00e4tsklinikum Schleswig-Holstein, Kiel<\/p>\n

1999-2004 Assistenzarzt am Institut f\u00fcr Pathologie, Universit\u00e4tsklinikum Schleswig-Holstein, Kiel<\/p>\n

2004-2005 Oberarzt am Institut f\u00fcr Pathologie, Universit\u00e4tsklinikum Schleswig-Holstein, Kiel<\/p>\n

2007 Fakultative Weiterbildung\/Zusatzbezeichnung: Molekularpathologie<\/p>\n

2008 leitender Oberarzt am Institut f\u00fcr Pathologie, Universit\u00e4tsklinikum T\u00fcbingen, T\u00fcbingen<\/p>\n

2013 Stellvertretender \u00e4rztlicher Direktor am Institut f\u00fcr Pathologie und Neuropathologie, Universit\u00e4tsklinikum T\u00fcbingen, T\u00fcbingen<\/p>\n

2018 Wissenschaftlicher Mitarbeiter (Teilzeit), Medizinische Klinik VIII, Klinik f\u00fcr Onkologie und Pulmonologie, UKT<\/p>\n

2018 Gesellschafter der Berufsaus\u00fcbungsgemeinschaft f\u00fcr Pathologie und Molekularpathologie Sipos & Weiler, Stuttgart<\/p>\n

2019 Gesch\u00e4ftsf\u00fchrer und Gesellschafter TBAG Molekulare Pathologie Baden-W\u00fcrttemberg GbR<\/p>\n

2019 Referenzpathologe, NET Zentrum, UKT<\/p>\n

2020 Wissenschaftlicher Leiter, ENETS Center o Excellence, UKT<\/p>\n

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DIAGNOSTISCHE SCHWERPUNKTE<\/strong><\/h4>\n

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Gastointestinale Pathologie, insbesondere Pankreas- und Lebererkrankungen
Neuroendokrine Neoplasien
Uropathologie, HNO- und Lungenerkrankungen
Weichteiltumoren und molekulare Pathologie<\/p>\n

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MITGLIEDSCHAFTEN<\/strong><\/h4>\n

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European Pancreatic Club
International Association of Pancreatology
Deutscher Pankreasclub
International Academy of Pathology, Deutsche Division
Deutsche Gesellschaft f\u00fcr Pathologie
American Association of Cancer Research
Bundesverband Deutscher Pathologen
Vorstand des Neuroendokrinen Tumor Registers<\/p>\n

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QUALIFIKATIONEN<\/strong><\/h4>\n

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1994 Facharzt f\u00fcr Pathologie und Zytopathologie, Ungarn
2001 Facharzt f\u00fcr Pathologie, Deutschland
2007 Fakultative Weiterbildung\/Zusatzbezeichnung: Molekularpathologie<\/p>\n

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Fortbildungst\u00e4tigkeiten (Auswahl)<\/strong><\/h3>\n

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SEIT 2009<\/strong><\/h4>\n

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Dozent \u201eDGVS Seminar Zertifikat Gastrointestinale Onkologie\u201c f\u00fcr Pankreas- und Lebertumoren<\/p>\n

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2012 – 2016<\/strong><\/h4>\n

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Halbtagsseminar \u201eZystische Pankreastumoren\u201c an der Symposion der Deutschen Division der International Academy of Pathology<\/p>\n

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2017<\/strong><\/h4>\n

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Neuroendocrine Tumors of the Gastrointestinal Tract \u2013 European School of Pathology, Varna<\/p>\n

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Publikationen<\/h2>\n

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Originalarbeiten: 145 (Impact Factor >920)
\u00dcbersichten: 19
Buchbeitr\u00e4ge: 12<\/p>\n

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Bucheintr\u00e4ge (aktuelle Auswahl)<\/strong><\/h3>\n

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WHO Classification Genetic Tumour Syndromes 2023
WHO Classification Endocrine and Neuroendocrine Tumors 2023
Diagnostic Histopathology of Tumors Ed. CDM Fletcher, 5th Edition 2019
WHO Classification of Tumours of the Digestive System, 4th Edition 2019
WHO Classification of Endocrine Organs, 4th Edition 2017
WHO Classification Endocrine Tumors 2017
Zystische Neoplasien des Pankreas: Histologische Klassifikation zystischer Pankreastumoren in DGIM Innere Medizin herausgegeben von Hendrik Lehnert 2015<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=“1″ module_id=“veroeffentlichungen“ _builder_version=“4.27.4″ _module_preset=“default“ locked=“off“ collapsed=“on“ global_colors_info=“{}“][et_pb_row _builder_version=“4.27.4″ _module_preset=“default“ width=“90%“ custom_margin=“||||false|false“ custom_padding=“||0px||false|false“ global_colors_info=“{}“][et_pb_column type=“4_4″ _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“][et_pb_text _builder_version=“4.27.4″ _module_preset=“default“ header_3_font_size=“26px“ global_colors_info=“{}“]<\/p>\n

Ver\u00f6ffentlichungen (aktuelle Auswahl)<\/strong><\/h3>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=“1_3,2_3″ _builder_version=“4.27.4″ _module_preset=“default“ width=“90%“ custom_margin=“||||false|false“ custom_padding=“||0px||false|false“ global_colors_info=“{}“][et_pb_column type=“1_3″ _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“][\/et_pb_column][et_pb_column type=“2_3″ _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“][et_pb_text _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“]<\/p>\n

Clinical characteristics and treatment patterns of patients with gastroenteropancreatic neuroendocrine neoplasia in Germany receiving peptide receptor radionuclide therapy: A real-world data registry-based study. Medicine (Baltimore).
<\/strong>von Hessert-Vaudoncourt C, Maasberg S, Begum N, Rinke A, P\u00f6ppel T, Sipos B<\/strong>, Grohe C, Fottner C, Stintzing S, Grabowski P
German NET Registry. 2025 Mar 14;104(11):e41853. doi: 10.1097\/MD.0000000000041853. PMID: 40101049; PMCID: PMC11922424.<\/p>\n

A real-world observation of patients with glioblastoma treated with a personalized peptide vaccine
<\/strong>Latzer P, Zelba H, Battke F, Reinhardt A, Shao B, Bartsch O, Rabsteyn A, Harter J, Schulze M, Okech T, Golf A, Kyzirakos-Feger C, Kayser S, Pieper N, Feldhahn M, W\u00fcnsche J, Seitz C, Hadaschik D, Garbe C, Hauser TK, la Foug\u00e8re C, Biskup D, Brooke D, Parker D, Martens UM, Illerhaus G, Blumenthal DT, Merrell R, Lorenzo LS, Hidv\u00e9gi M, de Robles P, Kebir S, Li WW, Li VW, Williams M, Miller AM, Kesari S, Castro M, Desjardins A, Ashley DM, Friedman HS, Wen PY, Neil EC, Iwamoto FM, Sipos B<\/strong>, Geletneky K, Zender L, Glas M, Reardon DA, Biskup S.
Nat Commun. 2024 Aug 11;15(1):6870<\/p>\n

First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure <\/strong>Zwirner S, Abu Rmilah AA, Klotz S, Pfaffenroth B, Kloevekorn P, Moschopoulou AA, Schuette S, Haag M, Selig R, Li K, Zhou W, Nelson E, Poso A, Chen H, Amiot B, Jia Y, Minshew A, Michalak G, Cui W, Rist E, Longerich T, Jung B, Felgendreff P, Trompak O, Premsrirut PK, Gries K, Muerdter TE, Heinkele G, Wuestefeld T, Shapiro D, Weissbach M, Koenigsrainer A, Sipos B<\/strong>, Ab E, Zacarias MO, Theisgen S, Gruenheit N, Biskup S, Schwab M, Albrecht W, Laufer S, Nyberg S, Zender L.
Cell. 2024 Mar 28;187(7):1666-1684.e26.<\/p>\n

Radiosensitizing Favors Response to Peptide Receptor Radionuclide Therapy in Patients With Highly Proliferative Neuroendocrine Malignancies: Preliminary Evidence From a Clinical Pilot Study
<\/strong>Trautwein NF, Hinterleitner C, Kiefer LS, Singer S, Mattern S, Schwenck J, Reischl G, Sipos B<\/strong>, Lauer UM, Dittmann H, Zender L, la Foug\u00e8re C, Hinterleitner M.
Clin Nucl Med. 2024 Mar 1;49(3):207-214<\/p>\n

Treatment modalities favoring outcome in well-differentiated neuroendocrine tumors G3.
<\/strong>Hinterleitner M, Pfeiffer R, Trautwein NF, Sipos B<\/strong>, Singer S, Nadalin S, K\u00f6nigsrainer A, Lauer UM, la Foug\u00e8re C, Zender L, Hinterleitner C.
Front Endocrinol (Lausanne). 2024 Jan 8;14:1285529.<\/p>\n

Multiple neuroendokrine Tumoren des Pankreas [Multiple neuroendocrine tumors of the pancreas].
Sipos B<\/strong>.
Pathologie (Heidelb). 2024 Feb;45(1):28-34. German.<\/p>\n

Network-targeting combination therapy of leptomeningeal glioblastoma using multiple synthetic lethal strategies: a case report.
<\/strong>Castro MP, Sipos B<\/strong>, Biskup S, Kahn N.
Front Oncol. 2023 Oct 31;13:1210224.<\/p>\n

Glucagon cell hyperplasia and neoplasia: a recently recognized endocrine receptor disease.
Sipos B<\/strong>, Kl\u00f6ppel G
Endocr Relat Cancer. 2023 Jul 18;30(8):e230032.<\/p>\n

MYC determines lineage commitment in KRAS-driven primary liver cancer development.
<\/strong>D’Artista L, Moschopoulou AA, Barozzi I, Craig AJ, Seehawer M, Herrmann L, Minnich M, Kang TW, Rist E, Henning M, Klotz S, Heinzmann F, Harbig J, Sipos B<\/strong>, Longerich T, Eilers M, Dauch D, Zuber J, Wang XW, Zender L. J Hepatol.
2023 Jul;79(1):141-149..<\/p>\n

Novel preclinical gastroenteropancreatic neuroendocrine neoplasia models demonstrate the feasibility of mutation-based targeted therapy.<\/strong>
Viol F, Sipos<\/strong> B<\/strong>, Fahl M, Clauditz TS, Amin T, Kriegs M, Nieser M,
Izbicki JR, Huber S, Lohse AW, Schrader J.
Cell Oncol (Dordr). 2022 Dec;45(6):1401-1419.
Analysis on the healing of gastrointestinal ulceration by using Hemospray
Werner CR, Br\u00fccklmeier L, Kratt T, Malek NP, Sipos B,
Wichmann D, G\u00f6tz M.
Sci Rep. 2021 Sep 24;11(1):19050.<\/p>\n

FGF-Receptors and PD-L1 in Anaplastic and Poorly Differentiated Thyroid Cancer: Evaluation of the Preclinical Rationale.<\/strong>
Adam P, Kircher S, Sbiera I, Koehler VF, Berg E, Kn\u00f6sel T, Sandner B, Fenske WK, Bl\u00e4ker H, Smaxwil C, Zielke A, Sipos B<\/strong>, Allelein S, Schott M,
Dierks C, Spitzweg C, Fassnacht M, Kroiss M.
Front Endocrinol (Lausanne). 2021 Aug 12;12:712107.<\/p>\n

Combined effects of PNPLA3, TM6SF2 and HSD17B13 variants on severity of biopsy-proven non-alcoholic fatty liver disease.<\/strong>
Paternostro R, Staufer K, Traussnigg S, St\u00e4ttermayer AF, Halilbasic E, Keritam O, Meyer EL, Stift J, Wrba F, Sipos B<\/strong>, Canbay A, Schlattjan M,
Aigner E, Datz C, Stickel F, Schafmayer C, Hampe J, Buch S, Prager G,
Munda P, Mandorfer M, Ferenci P, Trauner M.
Hepatol Int. 2021 Aug;15(4):922-933. doi: 10.1007\/s12072-021-10200-y. Epub 2021 Jun 2.<\/p>\n

CUX1 Enhances Pancreatic Cancer Formation by Synergizing with KRAS and Inducing MEK\/ERK-Dependent Proliferation<\/strong>
Griesmann H, M\u00fchl S, Riedel J, Theuerkorn K, Sipos B<\/strong>, Esposito I, Vanden, Heuvel GB, Michl P.
Cancers (Basel). 2021, May 18;13(10):2462.<\/p>\n

Platelet-Expressed Synaptophysin (pSyn) as Novel Biomarker in Neuroendocrine Malignancies. Cancers (Basel).<\/strong>
Hinterleitner M, Sipos B<\/strong>, Wagner V, Grottenthaler JM, Lauer UM,
Zender L, Hinterleitner C.
2021 May 11;13(10):2286.<\/p>\n

Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells.<\/strong>
Wiedenmann S, Cohrs CM, Perkhofer L, Jain G, Kr\u00fcger J, Hermann PC, Schmid M,Mad\u00e1csy T, Varga \u00c1, Griger J, Azoitei N, M\u00fcller M, Wessely O, Robey PG, Heller,S, Dantes Z, Reichert M, G\u00fcnes C, Bolenz C, Kuhn F, Mal\u00e9th J, Speier S, Liebau, S, Sipos B<\/strong>, Kuster B, Seufferlein T, Rad R, Meier M, Hohwieler M, Kleger A.
Cell Stem Cell. 2021 Jun 3;28(6):1105-1124.e19.<\/p>\n

Exploiting the MUC5AC Antigen for Noninvasive Identification of Pancreatic Cancer.<\/strong>
Henry KE, Shaffer TM, Mack KN, Ring J, Ogirala A, Klein-Scory S,
Eilert-Micus C, Schmiegel W, Bracht T, Sitek B, Clyne M, Reid CJ, Sipos B<\/strong>,
Lewis JS, Kalthoff H, Grimm J.
J Nucl Med. 2021 Oct;62(10):1384-1390.<\/p>\n

Unraveling the Molecular Tumor-Promoting Regulation of Cofilin-1 in Pancreatic Cancer.<\/strong>
Werle SD, Schwab JD, Tatura M, Kirchhoff S, Szekely R, Diels R,
Ikonomi N, Sipos B<\/strong>, Sperveslage J, Gress TM, Buchholz M, Kestler HA.
Cancers (Basel). 2021 Feb 10;13(4):725<\/p>\n

An IgG-based bispecific antibody for improved dual targeting in PSMA-positive cancer.<\/strong>
Zekri L, Vogt F, Osburg L, M\u00fcller S, Kauer J, Manz T, Pfl\u00fcgler M, Maurer A, Heitmann JS, Hagelstein I, M\u00e4rklin M, H\u00f6rner S, Todenh\u00f6fer T,
Calaminus C, Stenzl A, Pichler B, la Foug\u00e8re C, Schneider MA, Rammensee HG, Zender L,
Sipos B<\/strong>, Salih HR, Jung G.
EMBO Mol Med. 2021 Feb 5;13(2):e11902.<\/p>\n

Immunoprofiling in Neuroendocrine Neoplasms Unveil Immunosuppressive Microenvironment.<\/strong>
Busse A, Mochmann LH, Spenke C, Arsenic R, Briest F, J\u00f6hrens K,
Lammert H, Sipos B<\/strong>, K\u00fchl AA, Wirtz R, Pavel M, Hummel M,
Kaemmerer D, Baum RP, Grabowski P.
Cancers (Basel). 2020 Nov 19;12(11):3448.<\/p>\n

Elevated Serum Amino Acids Induce a Subpopulation of Alpha Cells to Initiate Pancreatic Neuroendocrine Tumor Formation.<\/strong>
Smith DK, Kates L, Durinck S, Patel N, Stawiski EW, Kljavin N, Foreman O, Sipos B<\/strong>, Solloway MJ, Allan BB, Peterson AS.
Cell Rep Med. 2020 Aug 25;1(5):100058.<\/p>\n

Targeting interleukin 6 signaling by monoclonal antibody siltuximab on cholangiocarcinoma.<\/strong>
J Nguyen MLT, Bui KC, Scholta T, Xing J, Bhuria V, Sipos B<\/strong>, Wilkens L,
Nguyen Linh T, Velavan TP, Bozko P, Plentz RR.
Gastroenterol Hepatol. 2021 May;36(5):1334-1345.<\/p>\n

Necroptosis microenvironment directs lineage commitment in liver cancer.<\/strong>
Seehawer M, Heinzmann F, D\u2019Artista L, Harbig J, Roux PF, Hoenicke L, Dang H, Klotz S, Robinson L, Dor\u00e9 G, Rozenblum N, Kang TW, Chawla R, Buch T, Vucur M, Roth M, Zuber J, Luedde T, Sipos B<\/strong>, Longerich T, Heikenw\u00e4lder M, Wang XW, Bischof O, Zender L.
Nature. 2018 Oct;562(7725):69-75.<\/p>\n

S2k-Leitlinie Neuroendokrine Tumore AWMF-Reg. 021-27<\/strong>
Deutsche Gesellschaft f\u00fcr Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS); Netzwerk Neuroendokrine Tumoren (NeT) e.V. (Patientenvertretung); Bundesorganisation Selbsthilfe NeuroEndokrine Tumoren e.V. (NET-sgh) (Patientenvertretung); Deutsche Gesellschaft f\u00fcr H\u00e4matologie und Medizinische Onkologie e.V. (DGHO), und Arbeitsgemeinschaft Internistische Onkologie (AIO) der Deutschen Krebsgesellschaft e.V; Deutsche Gesellschaft f\u00fcr Allgemein- und Viszeralchirurgie e.V. (DGAV); Deutsche Gesellschaft f\u00fcr Chirurgie (DGCH); Deutsche Gesellschaft f\u00fcr Endoskopie und Bildgebende Verfahren (DGEBV); Deutsche Gesellschaft f\u00fcr Nuklearmedizin e.V. (DGNM); Deutsche Gesellschaft f\u00fcr Innere Medizin (DGIM); Deutsche Gesellschaft f\u00fcr Endokrinologie (DGE); Deutsche Gesellschaft f\u00fcr Palliativmedizin e.V. (DGP); Deutsche R\u00f6ntgengesellschaft e.V. (DRG); Deutsche Gesellschaft f\u00fcr Pathologie e.V.\/Bundesverband Deutscher Pathologen (DGP\/BDP); Deutsche Gesellschaft f\u00fcr interventionelle Radiologie (DGiR); Authors; Collaborators:.
Z Gastroenterol. 2018 Jun;56(6):583-681. Epub 2018 Jun 11. German.<\/p>\n

Therapeutic Targeting of Tumor-Associated Macrophages in Pancreatic Neuroendocrine Tumors.<\/strong>
Krug S, Abbassi R, Griesmann H, Sipos B<\/strong>, Wiese D, Rexin P, Blank A, Perren A, Haybaeck J, H\u00fcttelmaier S, Rinke A, Gress TM, Michl P.
Int J Cancer. 2018 Apr 26. [Epub ahead of print]<\/p>\n

Pancreatic neuroendocrine carcinomas reveal a closer relationship to ductal adenocarcinomas than to neuroendocrine tumors G3.<\/strong>
Konukiewitz B, Jesinghaus M, Steiger K, Schlitter AM, Kasajima A,
Sipos B<\/strong>, Zamboni G, Weichert W, Pfarr N, Kl\u00f6ppel G.
Hum Pathol. 2018 Jul;77:70-79.. Epub 2018 Mar 26.<\/p>\n

[Neuroendocrine neoplasms of the auditory, olfactory, and visual sensory organs].<\/strong>
Sipos B<\/strong>.
Pathologe. 2018 May;39(3):255-263.. Review. German.<\/p>\n

MAFA missense mutation causes familial insulinomatosis and diabetes mellitus.<\/strong>
Iacovazzo D, Flanagan SE, Walker E, Quezado R, de Sousa Barros FA, Caswell R, Johnson MB, Wakeling M, Br\u00e4ndle M, Guo M, Dang MN, Gabrovska P, Niederle B, Christ E, Jenni S, Sipos B<\/strong>, Nieser M, Frilling A, Dhatariya K, Chanson P, de Herder WW, Konukiewitz B, Kl\u00f6ppel G, Stein R, Korbonits M, Ellard S.
Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):1027-1032.<\/p>\n

Somatostatin receptor expression related to TP53 and RB1 alterations in pancreatic and extrapancreatic neuroendocrine neoplasms with a Ki67-index above 20.<\/strong>
Konukiewitz B, Schlitter AM, Jesinghaus M, Pfister D, Steiger K, Segler A, Agaimy A, Sipos B<\/strong>, Zamboni G, Weichert W, Esposito I, Pfarr N, Kl\u00f6ppel G.
Mod Pathol. 2017 Apr;30(4):587-598.<\/p>\n

ATM Deficiency Generating Genomic Instability Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Therapy-Induced DNA Damage.<\/strong>
Perkhofer L, Schmitt A, Romero Carrasco MC, Ihle M, Hampp S, Ruess DA, Hessmann E, Russell R, Lechel A, Azoitei N, Lin Q, Liebau S, Hohwieler M, Bohnenberger H, Lesina M, Alg\u00fcl H, Gieldon L, Schr\u00f6ck E, Gaedcke J, Wagner M, Wiesm\u00fcller L, Sipos B<\/strong>, Seufferlein T, Reinhardt HC, Frappart PO, Kleger A.
Cancer Res. 2017 Oct 15;77(20):5576-5590.<\/p>\n

Defects in myosin VB are associated with a spectrum of previously undiagnosed low \u03b3-glutamyltransferase cholestasis.<\/strong>
Qiu YL, Gong JY, Feng JY, Wang RX, Han J, Liu T, Lu Y, Li LT, Zhang MH, Sheps JA, Wang NL, Yan YY, Li JQ, Chen L, Borchers CH, Sipos B<\/strong>, Knisely AS, Ling V, Xing QH, Wang JS.
Hepatology. 2017 May;65(5):1655-1669.<\/p>\n

Expression of DRD2 Is Increased in Human Pancreatic Ductal Adenocarcinoma and Inhibitors Slow Tumor Growth in Mice.<\/strong>
Jandaghi P, Najafabadi HS, Bauer AS, Papadakis AI, Fassan M, Hall A, Monast A, von Knebel Doeberitz M, Neoptolemos JP, Costello E, Greenhalf W, Scarpa A, Sipos B<\/strong>, Auld D, Lathrop M, Park M, B\u00fcchler MW, Strobel O, Hackert T, Giese NA, Zogopoulos G, Sangwan V, Huang S, Riazalhosseini Y, Hoheisel JD.
Gastroenterology. 2016 Dec;151(6):1218-1231.<\/p>\n

RelA regulates CXCL1\/CXCR2-dependent oncogene-induced senescence in murine Kras-driven pancreatic carcinogenesis.<\/strong>
Lesina M, W\u00f6rmann SM, Morton J, Diakopoulos KN, Korneeva O, Wimmer M, Einw\u00e4chter H, Sperveslage J, Demir IE, Kehl T, Saur D, Sipos B<\/strong>, Heikenw\u00e4lder M, Steiner JM, Wang TC, Sansom OJ, Schmid RM, Alg\u00fcl H.
J Clin Invest. 2016 Aug 1;126(8):2919-32.<\/p>\n

Loss of Chromosome 18 in Neuroendocrine Tumors of the Small Intestine: The Enigma Remains.<\/strong>
Nieser M, Henopp T, Brix J, Sto\u00df L, Sitek B, Naboulsi W, Anlauf M, Schlitter AM, Kl\u00f6ppel G, Gress T, Moll R, Bartsch DK, Heverhagen AE, Knoefel WT, Kaemmerer D, Haybaeck J, Fend F, Sperveslage J, Sipos B<\/strong>.
Neuroendocrinology. 2017;104(3):302-312.<\/p>\n

The role of integrins in primary and secondary brain tumors.<\/strong>
Schittenhelm J, Tabatabai G, Sipos B<\/strong>.
Histol Histopathol. 2016 Oct;31(10):1069-78. Review.<\/p>\n

Pharmacological macrophage inhibition decreases metastasis formation in a genetic model of pancreatic cancer.<\/strong>
Griesmann H, Drexel C, Milosevic N, Sipos B<\/strong>, Rosendahl J, Gress TM, Michl P.
Gut. 2017 Jul;66(7):1278-1285.<\/p>\n

Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.<\/strong>
Mazur PK, Herner A, Mello SS, Wirth M, Hausmann S, S\u00e1nchez-Rivera FJ, Lofgren SM, Kuschma T, Hahn SA, Vangala D, Trajkovic-Arsic M, Gupta A, Heid I, No\u00ebl PB, Braren R, Erkan M, Kleeff J, Sipos B<\/strong>, Sayles LC, Heikenwalder M, He\u00dfmann E, Ellenrieder V, Esposito I, Jacks T, Bradner JE, Khatri P, Sweet-Cordero EA, Attardi LD, Schmid RM, Schneider G, Sage J, Siveke JT. Nat Med. 2015 Oct;21(10):1163-71.<\/p>\n

Glucagon cell hyperplasia and neoplasia with and without glucagon receptor mutations.<\/strong>
Sipos B<\/strong>, Sperveslage J, Anlauf M, Hoffmeister M, Henopp T, Buch S, Hampe J, Weber A, Hammel P, Couvelard A, H\u00f6bling W, Lieb W, Boehm BO, Kl\u00f6ppel G.
J Clin Endocrinol Metab. 2015 May;100(5):E783-8.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=“1″ module_id=“gutachtertaetigkeit“ _builder_version=“4.27.4″ _module_preset=“default“ locked=“off“ global_colors_info=“{}“][et_pb_row _builder_version=“4.27.4″ _module_preset=“default“ width=“90%“ custom_margin=“||||false|false“ custom_padding=“||0px||false|false“ global_colors_info=“{}“][et_pb_column type=“4_4″ _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“][et_pb_text _builder_version=“4.27.4″ _module_preset=“default“ header_3_font_size=“26px“ global_colors_info=“{}“]<\/p>\n

Gutachtert\u00e4tigkeit (aktuelle Auswahl)<\/strong><\/h3>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=“1_3,2_3″ _builder_version=“4.27.4″ _module_preset=“default“ width=“90%“ custom_margin=“||||false|false“ custom_padding=“||0px||false|false“ global_colors_info=“{}“][et_pb_column type=“1_3″ _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“][\/et_pb_column][et_pb_column type=“2_3″ _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“][et_pb_text _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“]<\/p>\n

Cancer UK, Deutsche Forschungsgemeinschaft, Deutsche Krebshilfe, Berner Krebsliga<\/p>\n

Virchows Archiv, Pancreas, Arthritis Research and Therapy, European Journal of Gastroenterology & Hepatology<\/p>\n

Der Pathologe, BMC Cancer, Endocrine Related Cancer, Cancer Research, Expert Review Mol Diag, Histopathology<\/p>\n

International Journal of Cancer, International Journal of Legal Medicine, PLOS ONE, Molecular Cancer<\/p>\n

Journal of Cancer, Research and Clinical Oncology, Neoplasia<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=“1″ module_id=“kommission-molekularpathologie-bdp“ _builder_version=“4.27.4″ _module_preset=“default“ locked=“off“ global_colors_info=“{}“][et_pb_row _builder_version=“4.27.4″ _module_preset=“default“ width=“90%“ custom_margin=“||||false|false“ custom_padding=“||0px||false|false“ global_colors_info=“{}“][et_pb_column type=“4_4″ _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“][et_pb_text module_id=“kommission-molekularpathologie-bdp“ _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“]<\/p>\n

Kommission Molekularpathologie, BDP<\/h2>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=“1_3,2_3″ _builder_version=“4.27.4″ _module_preset=“default“ width=“90%“ custom_margin=“||||false|false“ custom_padding=“||0px||false|false“ global_colors_info=“{}“][et_pb_column type=“1_3″ _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“][\/et_pb_column][et_pb_column type=“2_3″ _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“][et_pb_text _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“]<\/p>\n

Prof. Dr. Sipos ist Gr\u00fcnder und seit 2025 Ko-Vorsitzender der Kommission Molekularpathologie am BDP<\/strong><\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=“1″ module_id=“referenzpathologie“ _builder_version=“4.27.4″ _module_preset=“default“ locked=“off“ global_colors_info=“{}“][et_pb_row _builder_version=“4.27.4″ _module_preset=“default“ width=“90%“ custom_margin=“||||false|false“ custom_padding=“||0px||false|false“ global_colors_info=“{}“][et_pb_column type=“4_4″ _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“][et_pb_text _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“]<\/p>\n

Referenzpathologie<\/h2>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=“1_3,2_3″ _builder_version=“4.27.4″ _module_preset=“default“ width=“90%“ custom_margin=“||||false|false“ custom_padding=“||0px||false|false“ global_colors_info=“{}“][et_pb_column type=“1_3″ _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“][\/et_pb_column][et_pb_column type=“2_3″ _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“][et_pb_text _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“]<\/p>\n

Referenzpathologische Begutachtung von pankreatischen und neuroendokrinen Neoplasien seit 2020 (auch ENETS Center of Excellence, Universit\u00e4tsklinikum T\u00fcbingen).<\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=“4.27.4″ _module_preset=“default“ width=“90%“ custom_margin=“40px||||false|false“ locked=“off“ global_colors_info=“{}“][et_pb_column type=“4_4″ _builder_version=“4.27.4″ _module_preset=“default“ global_colors_info=“{}“][et_pb_button button_url=“@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjIyOTYxNSJ9fQ==@“ button_text=“zur\u00fcck zum \u00c4rzte-Team“ _builder_version=“4.27.4″ _dynamic_attributes=“button_url“ _module_preset=“default“ custom_button=“on“ button_text_color=“#0092BB“ button_font=“|700|||||||“ button_icon=“||fa||900″ button_icon_color=“#0092BB“ button_icon_placement=“left“ animation_style=“slide“ animation_direction=“bottom“ global_colors_info=“{}“ button_bg_color__hover_enabled=“on|hover“ button_bg_color__hover=“#FFFFFF“ button_bg_enable_color__hover=“on“][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

Prof. dr. med. Bence Sipos Gesellschafter Qualipath Facharzt f\u00fcr Pathologie Molekularpathologie Fachbezogene Humangenetische Beratung

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<\/div>\n <\/div>\n <\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>VitaSTUDIUM1984-1990 Semmelweis Universit\u00e4t. Budapest, Ungarn (Humanmedizin)FACHARZT1994 Facharzt f\u00fcr Pathologie und Zytopathologie, Ungarn 2001 Facharzt f\u00fcr Pathologie, […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":229615,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"dipi_cpt_category":[],"class_list":["post-229608","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.qualipath.de\/nuertingen\/wp-json\/wp\/v2\/pages\/229608","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.qualipath.de\/nuertingen\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.qualipath.de\/nuertingen\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.qualipath.de\/nuertingen\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.qualipath.de\/nuertingen\/wp-json\/wp\/v2\/comments?post=229608"}],"version-history":[{"count":18,"href":"https:\/\/www.qualipath.de\/nuertingen\/wp-json\/wp\/v2\/pages\/229608\/revisions"}],"predecessor-version":[{"id":230411,"href":"https:\/\/www.qualipath.de\/nuertingen\/wp-json\/wp\/v2\/pages\/229608\/revisions\/230411"}],"up":[{"embeddable":true,"href":"https:\/\/www.qualipath.de\/nuertingen\/wp-json\/wp\/v2\/pages\/229615"}],"wp:attachment":[{"href":"https:\/\/www.qualipath.de\/nuertingen\/wp-json\/wp\/v2\/media?parent=229608"}],"wp:term":[{"taxonomy":"dipi_cpt_category","embeddable":true,"href":"https:\/\/www.qualipath.de\/nuertingen\/wp-json\/wp\/v2\/dipi_cpt_category?post=229608"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}